Noopept, courtesy Lazer76 at the Neanderhall:
The effect of new nootropic dipeptides–noopept (N-phenylacetyl-L-prolylglycine, GVS-111) and its metabolite (cyclo-L-prolylglycine)–and a standard nootrope piracetam on the transcallosal evoked potential (TEP) in rat brain was studied. In the dose range from 150 to 300 mg/kg, piracetam increased the TEP amplitude, which exhibited a maximum after 1.5-2 h and then gradually decreased. Both noopept and cyclo-L-prolylglycine also increased the TEP amplitude, which attained a plateau and retained this level over the entire observation time (above 3.5 h). All the nootropes studied increased both components of the evoked potential. Piracetam and cyclo-L-prolylglycine led to an approximately equal increase in both waves, while noopept induced a somewhat greater increase in the negative TEP wave amplitude. It is suggested that the positive effect of noopept and cyclo-L-prolylglycine upon the interhemispheric signal transfer (indicated by the improved transcallosal response) can be considered as a potential neurophysiological basis for a positive drug influence on the behavioral level.
I’m entirely convinced that excellent interhemispherical communication is the basis of the much-sought “flow state” that we usually rely upon psychological tricks to achieve. The “true genius” archetypes who tend to have perfect or near-perfect memory always seem to have perfect corpus callosums, which is why so many of them can memorize encyclopedias without much effort. In addition, athletes in complex sports are probably on this stuff already. 20-foot jump shots under pressure are not as easy as Kobe makes them look. I’m not real savvy on drug tests, but I’m sure there’s more stuff on the market than you can reasonably test for.