A comment I left over at Vault-co.
Something connected to methylation switches on the ARNDT2 gene sets off a cascade that begins pulling genetic sequences for fundamental development from the archaic DRD chains. Once started, they begin to fall like dominos until they all run out. I suspect the body is saying “Something bad has happened to this kid who is currently running the Holocene candy-ass spearchucker model software. We may need to do a rollback and switch him to the original Ice Age supertank Model T version of hominids in order to prepare him for what appears to be a very rough environment he is growing up in.”
It’s been a while since I learned this, so I might be misremembering, but I believe this would have been right before a massive neuron die-off in normal infant development (~2yo). Babies have an enormous number of neurons (way more than adults), but most of them die in these events. To my mind, this would be analogous to the genetic shifts that occur when catastrophic events wipe out large portions of a breeding population, preferentially killing off some gene clusters. An example would be a group of hunter gatherers where the gatherers are all killed in a fire while the hunters are in another area, culling the gatherer genes.
If we follow the analogy, it would suggest that epigenetics could trigger a preference cascade right before such a neural extinction event, preferentially culling the “holocene-strategy” neurons. Something to think about.