The Atreides as owls and worms as serpents (i.e. denizens of primordial chaos, i.e. precognitive society) suggest that comsumption of the spice (generated from the worms) opens inroads to the subconsciousness and the overall story as owls conquering methods of access to the subconscious as a means of reevolving into spiders. It would explain why almost every DnD plot I write generates some faction obsessed with lineage at some point.
Include a pic of Herbert, he’s bulb

I owe that insight to Kojima, since Boktai 2 had a formative impact on me as a kid and you fight Jormungandr who forms its own Tower of Babel as the final boss